011 - ANA Comprehensive Autoimmune Panel (11 tests)

ANA Screen + 11 ANA Components

PROVIDER INITIATED TEST - The ANA Comprehensive Autoimmune Panel evaluates antinuclear antibodies (ANA) and specific ANA-associated autoantibodies that may be present in autoimmune or connective tissue disorders. ANA testing helps assess immune system activity when symptoms such as joint pain, fatigue, rashes, or unexplained inflammation are present. Reflex testing for specific autoantibodies can provide further insight into the type of autoimmune process involved.

The panel includes 11 tests:

ANA Screen: Initial screening test for antinuclear antibodies

Anti-dsDNA: Often associated with systemic lupus erythematosus (SLE)

Chromatin Antibodies: Linked to lupus and other autoimmune conditions

Ribosomal P Antibodies: Associated with lupus, including neurologic involvement

Sjogren’s Antibodies (SS-A / SS-B): Common in Sjögren’s syndrome and lupus

Smith (Sm) Antibodies: Highly specific for lupus

Sm/RNP Antibodies: Seen in mixed connective tissue disease

RNP Antibodies: Associated with connective tissue disorders

Centromere B Antibodies: Often linked to limited systemic sclerosis

Scleroderma Antibodies (Scl-70): Associated with systemic sclerosis

Jo-1 Antibodies: Linked to inflammatory muscle diseases