The Tissue Transglutaminase IgG test measures IgG antibodies directed against tissue transglutaminase, an enzyme involved in normal intestinal function. Elevated tTG IgG antibodies may be associated with celiac disease or gluten-related disorders, particularly in individuals with IgA deficiency.
This test is commonly used as part of a celiac disease evaluation when symptoms such as chronic diarrhea, abdominal pain, bloating, weight loss, or nutrient deficiencies are present. It is often ordered alongside tTG IgA and other celiac-related antibody tests for a comprehensive assessment.
Results are interpreted in conjunction with clinical findings and additional laboratory testing to support diagnosis and management decisions.
Tissue Transglutaminase IgG
The Tissue Transglutaminase IgG test measures IgG antibodies directed against tissue transglutaminase, an enzyme involved in normal intestinal function. Elevated tTG IgG antibodies may be associated with celiac disease or gluten-related disorders, particularly in individuals with IgA deficiency.
This test is commonly used as part of a celiac disease evaluation when symptoms such as chronic diarrhea, abdominal pain, bloating, weight loss, or nutrient deficiencies are present. It is often ordered alongside tTG IgA and other celiac-related antibody tests for a comprehensive assessment.
Results are interpreted in conjunction with clinical findings and additional laboratory testing to support diagnosis and management decisions.